If you suffer from psoriasis, you already know how frustrating it can be.
The redness. The itching. The flaky patches that just won’t seem to go away—especially during colder months or times of stress.
And while there’s no “cure,” there are products that can dramatically reduce flare-ups. Over the past few months, our team tested dozens of products—from steroid creams to natural supplements—and narrowed them down to 5 products that actually delivered noticeable relief.
Here’s what made the cut:
1. GLOW by RMDY Skin
Most creams try to manage psoriasis from the surface. GLOW flips that approach completely—by targeting the internal inflammation that often triggers skin flare-ups in the first place.
This daily supplement uses 6 clinically studied probiotic strains for skin health—like LGG® and BB536—to help rebalance the gut microbiome and calm systemic inflammation. In our testing, users consistently reported reduced redness, less itching, and smoother skin after 4–6 weeks of daily use. Several also noticed improvements in bloating and digestion—likely thanks to the gut-skin connection that’s becoming a major focus in dermatology.
What sets GLOW apart is the formula: it’s not just skin-focused probiotics. You also get skin-supportive nutrients like Zinc (for barrier strength), Vitamin A (for cell renewal), and Hyaluronic Acid (for hydration), plus Milk Thistle and Digestive Enzymes to support detox and absorption.
It's easy to take (2 capsules), requires no prescription, and comes with a 60-day money-back guarantee. For anyone looking for a non-topical, science-backed approach to calming psoriasis, this was our clear winner.
[EDIT: The owners are offering a Buy 2, Get 3rd FREE Deal for readers today.]test
2. Gladskin Eczema Cream with Micreobalance
At over $35 for a 1.7 oz tube, this is one of the priciest creams we tested—but the reviews are hard to ignore.
Gladskin uses a patented smart protein called Micreobalance® to rebalance skin bacteria without steroids or antibiotics. It’s made in Europe, dermatologically tested, and especially popular among people with both eczema and psoriasis.
We liked the light, non-greasy feel—and several testers said it noticeably reduced stinging and redness, especially on the face and neck. The downside? It doesn’t go far, and at this price point, full-body use gets expensive quickly.
If money isn’t a concern and you want an elegant, microbiome-friendly topical, this one’s worth a look. Just be ready to restock often.
3. MG217 Psoriasis Coal Tar Gel
This is one of the few over-the-counter products that still contains coal tar—a traditional but effective psoriasis treatment for stubborn plaques and scaling.
We were impressed by how well it worked for thick patches on elbows, knees, and scalp. The downside? It smells... not great. And the texture is a bit greasy.
If you’re looking for a spot treatment for chronic plaques, MG217 is worth having in your toolkit. But it’s not ideal for full-body use or people with sensitive skin. Think of it more like a “break-glass-in-case-of-flare-up” option.
Still, it might be worth a try. You can get MG217 here.
4. Aveeno Calm + Restore Oat Gel Moisturizer
For people with facial psoriasis or ultra-sensitive skin, Aveeno’s Calm + Restore line delivered surprisingly strong results.
The gel formula feels light but packs serious hydration, and the prebiotic oat extract seems to reduce redness and burning for many users. We didn’t see dramatic changes in plaque size, but there was a clear reduction in overall discomfort and irritation—especially when used as a base layer under heavier creams.
Not a cure by any means, but a very solid everyday moisturizer for fragile, flare-prone skin.
5. CeraVe Psoriasis Cleanser
This salicylic acid-based body wash won points for helping reduce scaling and rough texture over time. It also includes niacinamide and ceramides, both of which support skin barrier health.
Several of our testers used it in the shower daily and noticed less build-up on problem areas like knees and back. It’s not a standalone solution—but when paired with something like GLOW or a rich moisturizer, it’s a great supporting player.
You can get CeraVe here.
Bottom Line: What Actually Works?:
Most people with psoriasis know: there’s no magic pill. But the right combination of treatments—targeting both the inside and outside—can make a huge difference.
If you’re tired of chasing steroid creams, we strongly recommend trying GLOW by RMDY Skin. It’s gentle, backed by science, and actually works from within to reduce the inflammation that drives your flare-ups.
With 6 targeted probiotic strains, gut-healing nutrients, and a no-risk money-back guarantee—it’s earned our top spot for a reason.
